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The cyclic cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS)-stimulator of interferon genes (STING) pathway is important in innate immune response and has been linked to cardiovascular inflammation, remodeling, and degeneration. Cardiovascular diseases (CVDs) are a leading cause of death worldwide. Inflammation is a key factor in the development and progression of CVDs. The […]
From Prevention to Protection: 5 Power Moves for a Stronger, Healthier Heart
Over the course of a lifetime, the heart beats around 2.5 billion times, pumping millions of gallons of blood to every region of the body. This constant flow transports oxygen, fuel, hormones, other substances, and a slew of vital cells. It also transports metabolic waste products. When the heart stops beating, vital functions cease to […]
Epithelia Provoke Inflammation in Response to Apoptosis
Apoptosis is a process of programmed cell death that is traditionally considered to be immunologically silent. This means that it does not trigger an inflammatory response from the immune system. However, a new study has shown that apoptosis can actually provoke inflammation in zebrafish and cell culture when apoptotic epithelial cells cannot be expelled from […]