In 2018, the World Health Organization introduced “Disease X” as a potential global health threat caused by an unknown pathogen. Little did we know that the world would be grappling with the novel coronavirus, initially known as 2019-nCoV, just a year later. Researchers now propose renaming it “Transmissible Acute Respiratory Syndrome Coronavirus (TARS-CoV)” due to its rapid spread. Meanwhile, scientists are making strides in developing therapies, like broad-spectrum fusion inhibitors and neutralizing antibodies. These innovations offer hope in the fight against TARS-CoV and other emerging coronaviruses