Next-generation protein sequencing (NGS) is a powerful new technology that can analyse proteins more comprehensively and in detail. This can be a valuable tool for researchers in various fields, including biology, medicine, and forensics.
Related Posts
hnRNPU Regulation in Multiple Myeloma Sensitivity to Selinexor: Implications for Patient Stratification
Selinexor, a novel inhibitor for multiple myeloma (MM), faces limited research on resistance. Heterogeneous nuclear ribonucleoprotein U (hnRNPU) was identified as a regulator impacting MM’s response to selinexor. Comparing control knockdown (CTR-KD) and hnRNPU knockdown (hnR-KD) MM cells revealed increased selinexor-induced cell death in hnR-KD cells in vitro and in mice. Lower hnRNPU expression correlated […]
Unlocking the secrets of Protein function: Scientists Develop New Toolkit to Help Researchers Predict Protein Behaviour
A new tutorial published in the journal Nature Methods provides a comprehensive overview and comparison of 23 publicly available computational tools for predicting intrinsic disorder in proteins. The guide includes information on accuracy, runtime, availability, and the need for functional insights. It also provides examples and instructions for using the selected tools, as well as […]
Novel Halogenated Furanone Derivatives as Quorum Sensing Inhibitors
The overuse of antibiotics has led to multiple drug-resistant bacterial strains causing 16 million deaths annually. Bacterial biofilms, constituting 65% of infectious diseases, thrive via quorum sensing (QS). Inhibiting QS offers a promising strategy. Pseudomonas aeruginosa, a major nosocomial pathogen, employs AHLs (3OC12 and C4) for QS signaling, involving receptors QscR, LasR, and RhlR. Natural […]