Recent research indicates that mRNA vaccines, such as those developed against COVID-19, possess a remarkable ability to harness T-cell power specifically in combating the virus within the lungs. T-cells, a crucial component of the immune system, play a pivotal role in recognizing and eliminating infected cells. The mRNA vaccines, including those by Pfizer-BioNTech and Moderna, instruct cells to produce a spike protein found on the surface of the virus, prompting a robust immune response that involves T-cell activation. This targeted T-cell activity proves crucial in preventing severe respiratory manifestations of COVID-19, as the lungs are a primary site of infection. The findings underscore the multifaceted effectiveness of mRNA vaccines in conferring not only antibody protection but also engaging T-cell immunity, providing a more comprehensive defense against the virus and offering valuable insights for ongoing efforts in vaccine development and public health strategies.
The power of sugar chains can be harnessed to develop new cancer immunotherapy by targeting specific glycan structures on cancer cells. Glycans play a role in immune evasion, and modifying them can enhance the immune recognition of cancer cells. Researchers aim to design therapies that leverage these sugar chains to stimulate the immune system effectively, […]
Cytomegalovirus (CMV) is a common herpesvirus that most women contract unknowingly before reaching child-bearing age. It’s usually harmless except during pregnancy when, if passed on to the developing fetus, it is a leading cause of miscarriage and birth defects, including cerebral palsy and hearing loss. Researchers have long known that the risk for complications is […]
In a major breakthrough, scientists have discovered that certain immune cells, called macrophages, have the ability to change their shape to squeeze through tiny spaces and reach tumors more effectively. This remarkable ability of macrophages to shapeshift could explain why some cancer immunotherapies have been more successful than others. Scientists believe that understanding how macrophages […]