Combining neurologic and blood pressure drugs reduce breast tumor development in mice

According to a new study combining drugs used to treat bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high-fat diet fed to their mothers during pregnancy. Valproic acid was the main drug in the study protocol, which inhibits histone deacetylase (HDAC), an essential gene epigenetic silencer. The research finding indicates how impactful the addition or subtraction from DNA of an epigenetic methyl group can be along with the diet which plays a major role in cancer risk patients.

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