Scientists at Scripps Research have discovered a new way to fight age-related diseases. They found that a protein called DELE1 forms a cylindrical structure that is necessary to activate the cell’s integrated stress response (ISR). The ISR is a critical pathway that helps our cells maintain health, but it is impaired in many age-related diseases. The researchers believe that targeting the DELE1 protein could lead to new treatments for a range of diseases, such as neurodegenerative diseases, cancer, and heart disease.
A comprehensive review of 25 studies spanning nearly 50 years reveals a consistent association between insecticide exposure and diminished sperm concentration in adult men globally. The research, conducted by a team from Italy and the US, is considered the most thorough systematic analysis on the subject to date. Focusing on organophosphates and N-methyl carbamates, commonly […]
What are antibiotics? Antibiotics, also known as antibacterials, are category of medications which kills or slow down the bacterial growth. Penicillin was the first antibiotic, discovered by Sir Alexander Fleming in 1928, but it was not until the early 1940s that its true potential was recognized before it came into widespread use. In 1942, the […]
Apoptosis is a process of programmed cell death that is traditionally considered to be immunologically silent. This means that it does not trigger an inflammatory response from the immune system. However, a new study has shown that apoptosis can actually provoke inflammation in zebrafish and cell culture when apoptotic epithelial cells cannot be expelled from […]