Researchers at Memorial Sloan Kettering Cancer Center have created Spectra, a new open-source AI tool that enhances the analysis of single-cell transcriptomic data. Spectra can pinpoint important gene expression patterns amid technical noise, making it valuable for studying large patient groups, identifying meaningful patient characteristics, and discovering biomarkers and drug targets in immuno-oncology. The researchers offer Spectra for free, aiming to revolutionize single-cell transcriptomic data analysis and facilitate new biological discoveries worldwide.
Histidine methylation, a new post-translational modification, is not well understood. A recent study identified γ-enolase, a glycolytic enzyme subunit, as a new substrate for histidine methylation. The study found that methylation of the 190th histidine residue of γ-enolase is important for subunit dimerization and enolase activity. None of the three previously identified mammalian histidine methyltransferases […]
Ever wondered why that supermarket steak looks so mouthwateringly red while the one at the back seems a bit, well, off? Turns out, the color of fresh beef is more than just aesthetics – it’s a scientific symphony playing out right before your eyes! Scientists are using high-tech tools like mass spectrometry and proteomics to […]
Erucic acid is a byproduct of grease processing that is often wasted. However, new research has shown that it can be used to develop novel surfactants that have a wide range of potential applications. One such surfactant is adamantyl trimethylammonium erucate (AdEr). AdEr has been shown to have a lower critical micelle concentration (CMC) and […]