Multiple sentences are made by combining clauses. The simplest way of doing this is to use the grammatical equivalent of a plus sign:
She has not been very successful + she is looking for another career.
The commonest words to do this job are:
and but or
It is possible to string together as many clauses as you like in this way:
She has not been very successful and she is looking for another career, but so far she has not had much luck and has decided to try a different tack or even give up altogether, but . . . .
Until your readers either get lost or give up in disgust!
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