5 Steps for Publishing in a High-Quality Medical Journal

Scientific writing and publishing is a vital component of medical advancement. Publications are used to transmit new developments in human knowledge to the rest of the world. This knowledge must be accurate, valid, reproducible, and clinically valuable. Many ambitious physicians and scientists aspire to publish their work in high-impact publications.

 What are the Effective Steps for Publishing in a High-Quality Medical Journal?

Choose a Journal and Read the Journal’s Instructions.

It is critical to decide on authorship and the order of authors, including the corresponding author, ahead of time. 6 All authors listed on the final manuscript must have contributed substantially to the work to be held accountable and accept public accountability for the publication’s content. When preparing your paper, carefully observe the author guidelines, including the word limit and the number of tables and figures allowed. Many journals permit the submission of supplemental material as part of your publication, subject to the word count and figures/tables constraints.

Prepare the Manuscript

  • Organize the Manuscript – Begin by outlining the manuscript with this basic structure in mind. The first rough draft would be a list of crucial points to describe beneath each section and subsection.
  • Prepare the Manuscript – Pay attention when drafting the manuscript to avoid plagiarism (including self-plagiarism), fraud, and fabrication.
  • Colleagues should provide feedback and revise the manuscript – After completing the work, share it with co-authors and one or two non-author colleagues for criticism and feedback. Address and correct the English after revising to verify that your idea or ideas have been appropriately and fully communicated.


Submit the Manuscript

The majority of scientific journals now demand submissions be made through their websites. Most journals allow authors to propose reviewers who should and should not evaluate an article during the manuscript submission process. Such comments are beneficial to the editorial staff of the journals. Choose your title and keywords carefully so that readers can discover your paper. A brief cover letter that includes a two- to a three-sentence overview of the manuscript’s relevance might provide essential context to the editor.

Receive the Editor’s Communication and Revise the Manuscript

Acceptance of a paper as submitted is extremely rare. Do not be offended if your manuscript is rejected. In reality, only about one in every four articles is approved by a top journal. If adjustments are requested, it is critical to provide a thoughtful and respectful response to maximize the likelihood of later acceptance.

Resubmit the Manuscript

Include a cover letter to the editor with point-by-point responses to the reviewers’ remarks and ideas when submitting a revised manuscript, and address all complaints and suggestions as extensively as possible. It would help to highlight the Changes in the updated text to evaluate thoroughly.


To summarise, the process of publishing a manuscript in a high-impact journal begins with selecting an important question, designing a sound study with statistical power, carrying out the work with impeccable integrity and attention to detail, writing an excellent manuscript, submitting it to the appropriate journal, fully responding to reviewer comments, and completing the standard post-acceptance checks. Nothing beats the satisfaction of seeing your paper published and visible to the rest of the world.


6 Ways to Increase Manuscript Acceptance

The standard of your scientific activity is the publication of your study. Making your papers understandable and informative so that your peers can read and profit from them is the key to getting them accepted. Although scientific quality is paramount, clear and concise writing can often mean the difference between acceptance and rejection.


What are the Effective Ways to Increase the chance of acceptance of the manuscript?


Journal Selection

The journal you choose has a significant impact on how quickly you’ll be published. Check the spectrum of relevant publications while your study is being prepared for publication or even before. High Impact Journals can help you increase the number of times your research is published.


Follow the author guidelines. 

Make sure your manuscript is formatted correctly for the journal you’re submitting it to. Similarly, if you submit a manuscript to a new journal after it has been rejected by one, make sure to change your cover letter to reflect the new journal. When a journal editor sees one of their competitors’ names on the cover letter, it immediately turns them off, and it makes you appear sloppy and careless with details, which is not a good thing.


Write transparently.

Unfortunately, imprecise wording can hinder the publication of a well-designed study with significant consequences. Editors and reviewers, in particular, may struggle to comprehend the content and may have a negative prejudice against poorly written papers, making rejection more likely. For non-native English speakers, this is a challenging obstacle to overcome.


Check Plagiarism

Most submitted manuscripts are checked for plagiarism to guarantee that no already published content is published. Remember that you cannot just cut and paste words or chunks from previous papers, even if you repeat methods or other material from your previous works, because this is considered a kind of plagiarism known as self-plagiarism. Ensure that any borrowed information, including your own, is accompanied by a reference or reworded.


Write Clear Cover Letter

While a weak cover letter will not necessarily reduce your chances of being published, a strong cover letter will. Write a thoughtful cover letter that helps the editor rapidly grasp the impact of your research and how it will revolutionize thinking in your industry, rather than an introductory, generic cover letter that satisfies the bare-bones standards. Improve your chances of the editor being interested in your book by producing a clear, concise, and appealing cover letter.


Keep track of the journal.

If you submitted your article to a journal but have yet to hear back, you should contact the editor to inquire about the status of your submission. Because the time it takes for a journal to make a decision varies by field and journal, you may wish to check with colleagues or go to the journal’s website to see if you’ve been waiting longer than typical.








The pinnacle of your scientific activity is the publication of your study. Making your papers understandable and informative so that your peers can read and profit from them is the key to getting them accepted.

How to resurrect a rejected manuscript?

Rejection of your research paper by a journal does not necessarily imply that your research is fundamentally unsuitable for publication. This is because rejection depends on several factors that might not be solely linked to the main thrust of your research. Besides, the reviewers who evaluate your paper are not familiar with your credentials and therefore might not emphasize the positive factors in your paper. Therefore, it is important that you do not get disheartened or overly disappointed. With certain modifications and perseverance, it is definitely possible to resurrect your research and see it through to publication.

In fact, there are several positive takeaways from a rejection. The well-known chemistry journal Angewandte Chemie carried out a systematic study of the rejection procedure and concluded that most manuscripts do not go through large-scale modifications on their way from a rejection to eventual publication. Therefore, a rejection does not signify that your paper is beyond redemption. In fact, there is every chance that the paper will ultimately find its destined forum for publication.

On the other hand, a study by Vincent Calcagno, ecologist at the French Institute for Agricultural Research in Sophia-Antipolis, has concluded that a research paper goes through several iterations and modifications from the time of its first submission until its final acceptance. These changes contribute significantly to the improvement of the research. The study also observed that research papers that have gone through one or more rejections before publication tend to be cited more than those that have been published following their first submission. This trend is evident after about three to six years following publication.

Calcagno argues that the influence of peer reviews and the inputs from referees and editors makes papers better and each rejection improves the quality of the manuscript from the last attempt. There is also a theory among certain editors to “reject more, because more rejections improve quality.”

Therefore, instead of giving in to despair, it is important to patiently evaluate the reasons for rejection and the associated comments, and to act on them in future submissions of the paper. You can also take recourse to professional editing services to refine your manuscript and help in the submission of the paper to other journals.

The following are some guidelines for first-time writers in making their papers more acceptable:

  • Select an innovative and interesting research topic.
  • Ensure that your writing is well-organized and lucid as it flows from its aim to the conclusion through the methodology, results, and discussion sections.
  • Stay away from plagiarized text and ensure that your research is original and unpublished.
  • Select the most suitable journal that has a good scope for your research topic.
  • Follow the reviewer’s suggestions on your paper in case of a rejection, so that it is in better shape for the next submission.

In case the reviewers cite the reason of unsuitability of your research for the target journal, it is important to prepare and resubmit it to another more suitable journal. If it gets rejected again, keep working on your paper and make repeated attempts at submission until it gets accepted. After all, patience and perseverance are two important virtues of any writer. As the well-known 19th-century American writer Elbert Hubbard said, “A little more persistence, a little more effort, and what seemed hopeless failure may turn to glorious success.”